Derma Sciences Bioguard Antimicrobial Bandage Roll

SKU
G-9845
Derma Sciences Bioguard Antimicrobial Bandage Roll feature an antimicrobial agent--cationic biocide--that kills pathogens within Wound Care dressings. Manufactured by Derma Sciences, Derma Sciences Bioguard Antimicrobial Bandage Roll provide a barrier to bacterial penetration to the wound and protect patients from external contaminants. BioGuard Dressings protect caregivers from cross-contamination during wound changes. Derma Sciences Bioguard Antimicrobial Bandage Roll offer several advantageous over other antimicrobial dressings. BioGuard Antimicrobial Dressings are not toxic to good cells, they reduce the risk of leaching the antimicrobial agent out from the dressing to negatively affect the wound, and they reduce the risk of the antimicrobial agent forming resistant strains of pathogens. Derma Sciences Bioguard Antimicrobial Bandage Roll line of dressings features a strong cationic biocide known as poly diallyl dimethyl ammonium chloride or pDADMAC. When bound to wound dressings, pDADMAC disrupts pathogens’ cell walls in the following way: 1. Normal bacterial membranes are stabilized by Ca+2 ions binding anionic charged phospholipids. 2. pDADMAC rapidly displaces Ca+2 leading to loss of fluidity. 3. Domains in the membrane then undergo a transition to smaller micelles leading to membrane disruption. Derma Sciences Bioguard Antimicrobial Bandage Roll Derma Sciences Bioguard Antimicrobial Bandage Roll are tested for safety and biocompatibility. Direct dermal testing included skin irritation and sensitization, showing no irritation or sensitization. Sensitive in vitro models were used to assess cytotoxicity by multiple methods, including not only agar diffusion but also direct contact testing on fibroblast cell lines. The results demonstrate that BioGuard impeded cellular growth no more than negative controls, while a market leading silver dressing showed significant cytotoxicity in the same assay. Derma Sciences Bioguard Antimicrobial Bandage Rolls Features & Benefits Derma Sciences Bioguard Antimicrobial Bandage Roll are not toxic to good cells Reduces the risk of leaching the antimicrobial agent out from the dressing to negatively affect the wound Reduce the risk of the cationic biocide antimicrobial agent forming resistant strains of pathogens. Provides a barrier to bacterial penetration. Kills pathogens within the dressing.
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