Bactroban Cream Ointment 2%

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Bactroban, Bactroban Nasal 2%

Pharmacologic class: Dermatologic agent

Therapeutic class: Anti-infective, topical

Pregnancy risk category B

Action: Inhibits bacterial protein and RNA synthesis by reversibly and specifically binding to bacterial isoleucyl-transfer RNA synthetase. Bactericidal.
Availability:

Intranasal ointment: 2.15%

Topical cream: 2%

Topical ointment: 2%

Indications and dosages: Impetigo Adults and children ages 2 months to 16 years: Apply a small amount of ointment topically t.i.d. for 3 to 5 days. Reevaluate if no response. Infected traumatic skin lesions Adults and children ages 3 months to 16 years: Apply a small amount of cream topically t.i.d. for 10 days. Nasal colonization of methicillin-resistant Streptococcus aureus Adults and children ages 12 and older: Apply intranasal ointment (half of single-use tube to each nostril) topically to anterior nares b.i.d. for 5 days.
Contraindications Hypersensitivity to drug or its components
Precautions: Use cautiously in:

moderate or severe renal impairment (with large doses)

breastffeeding patients

children younger than age 12 (intranasal ointmment), younger than age 3 months (cream), or younger than age 2 months (ointment).